Cargando…
Complete Genome of the Chitin-Degrading Bacterium, Paenibacillus xylanilyticus W4
Chitinases possess an extraordinary ability to directly hydrolyze highly insoluble chitin polymers to low-molecular-weight chito-oligomers, which possess particular biological functions, such as elicitor action and antitumor activity. A novel strain, Paenibacillus xylanilyticus W4, which was isolate...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865854/ https://www.ncbi.nlm.nih.gov/pubmed/31670768 http://dx.doi.org/10.1093/gbe/evz241 |
_version_ | 1783472083551911936 |
---|---|
author | Liao, Weifang Liu, Pulin Liao, Weijie Miao, Lihong |
author_facet | Liao, Weifang Liu, Pulin Liao, Weijie Miao, Lihong |
author_sort | Liao, Weifang |
collection | PubMed |
description | Chitinases possess an extraordinary ability to directly hydrolyze highly insoluble chitin polymers to low-molecular-weight chito-oligomers, which possess particular biological functions, such as elicitor action and antitumor activity. A novel strain, Paenibacillus xylanilyticus W4, which was isolated from soil, showed strong chitin degradation activity. Here, we first reported the complete genome information of P. xylanilyticus. Paenibacillus xylanilyticus W4 contains a 5,532,141 bp single circular chromosome with 47.33% GC content. The genome contains 5,996 genes, including 39 rRNA- and 109 tRNA-coding genes. Phylogenetic analysis and Genome-to-Genome Distance revealed its taxonomic characterization into a separate family. Six glycoside hydrolase 18 (GH18) and 2 GH23 enzymes involved in chitin degradation. Although many of the chitinases were conserved in Paenibacillus, several GH18 chitinases share high similarity with Bacillus circulans. The genome information provided here could benefit for understanding the chitin-degrading properties of P. xylanilyticus as well as its potential application in biotechnological and pharmaceutical fields. |
format | Online Article Text |
id | pubmed-6865854 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-68658542019-11-25 Complete Genome of the Chitin-Degrading Bacterium, Paenibacillus xylanilyticus W4 Liao, Weifang Liu, Pulin Liao, Weijie Miao, Lihong Genome Biol Evol Genome Report Chitinases possess an extraordinary ability to directly hydrolyze highly insoluble chitin polymers to low-molecular-weight chito-oligomers, which possess particular biological functions, such as elicitor action and antitumor activity. A novel strain, Paenibacillus xylanilyticus W4, which was isolated from soil, showed strong chitin degradation activity. Here, we first reported the complete genome information of P. xylanilyticus. Paenibacillus xylanilyticus W4 contains a 5,532,141 bp single circular chromosome with 47.33% GC content. The genome contains 5,996 genes, including 39 rRNA- and 109 tRNA-coding genes. Phylogenetic analysis and Genome-to-Genome Distance revealed its taxonomic characterization into a separate family. Six glycoside hydrolase 18 (GH18) and 2 GH23 enzymes involved in chitin degradation. Although many of the chitinases were conserved in Paenibacillus, several GH18 chitinases share high similarity with Bacillus circulans. The genome information provided here could benefit for understanding the chitin-degrading properties of P. xylanilyticus as well as its potential application in biotechnological and pharmaceutical fields. Oxford University Press 2019-10-31 /pmc/articles/PMC6865854/ /pubmed/31670768 http://dx.doi.org/10.1093/gbe/evz241 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Genome Report Liao, Weifang Liu, Pulin Liao, Weijie Miao, Lihong Complete Genome of the Chitin-Degrading Bacterium, Paenibacillus xylanilyticus W4 |
title | Complete Genome of the Chitin-Degrading Bacterium, Paenibacillus xylanilyticus W4 |
title_full | Complete Genome of the Chitin-Degrading Bacterium, Paenibacillus xylanilyticus W4 |
title_fullStr | Complete Genome of the Chitin-Degrading Bacterium, Paenibacillus xylanilyticus W4 |
title_full_unstemmed | Complete Genome of the Chitin-Degrading Bacterium, Paenibacillus xylanilyticus W4 |
title_short | Complete Genome of the Chitin-Degrading Bacterium, Paenibacillus xylanilyticus W4 |
title_sort | complete genome of the chitin-degrading bacterium, paenibacillus xylanilyticus w4 |
topic | Genome Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865854/ https://www.ncbi.nlm.nih.gov/pubmed/31670768 http://dx.doi.org/10.1093/gbe/evz241 |
work_keys_str_mv | AT liaoweifang completegenomeofthechitindegradingbacteriumpaenibacillusxylanilyticusw4 AT liupulin completegenomeofthechitindegradingbacteriumpaenibacillusxylanilyticusw4 AT liaoweijie completegenomeofthechitindegradingbacteriumpaenibacillusxylanilyticusw4 AT miaolihong completegenomeofthechitindegradingbacteriumpaenibacillusxylanilyticusw4 |