Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons. While several pathogenic mutations have been identified, the vast majority of ALS cases have no family history of disease. Thus, for most ALS cases, the disease may be a p...

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Detalles Bibliográficos
Autores principales: Tam, Oliver H., Rozhkov, Nikolay V., Shaw, Regina, Kim, Duyang, Hubbard, Isabel, Fennessey, Samantha, Propp, Nadia, Fagegaltier, Delphine, Harris, Brent T., Ostrow, Lyle W., Phatnani, Hemali, Ravits, John, Dubnau, Josh, Hammell, Molly Gale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866666/
https://www.ncbi.nlm.nih.gov/pubmed/31665631
http://dx.doi.org/10.1016/j.celrep.2019.09.066

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