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Improved chemotherapy modeling with RAG-based immune deficient mice

We have previously characterized an acute myeloid leukemia (AML) chemotherapy model for SCID-based immune deficient mice (NSG and NSGS), consisting of 5 days of cytarabine (AraC) and 3 days of anthracycline (doxorubicin), to simulate the standard 7+3 chemotherapy regimen many AML patients receive. W...

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Detalles Bibliográficos
Autores principales:	Wunderlich, Mark, Manning, Nicole, Sexton, Christina, Sabulski, Anthony, Byerly, Luke, O’Brien, Eric, Perentesis, John P., Mizukawa, Benjamin, Mulloy, James C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867639/ https://www.ncbi.nlm.nih.gov/pubmed/31747424 http://dx.doi.org/10.1371/journal.pone.0225532

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