Cargando…
Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense
Macrophage-mediated phagocytosis and cytokine production represent the front lines of resistance to bacterial invaders. A key feature of this pro-inflammatory response in mammals is the complex remodeling of cellular metabolism towards aerobic glycolysis. Although the function of bactericidal macrop...
Autores principales: | Krejčová, Gabriela, Danielová, Adéla, Nedbalová, Pavla, Kazek, Michalina, Strych, Lukáš, Chawla, Geetanjali, Tennessen, Jason M, Lieskovská, Jaroslava, Jindra, Marek, Doležal, Tomáš, Bajgar, Adam |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867711/ https://www.ncbi.nlm.nih.gov/pubmed/31609200 http://dx.doi.org/10.7554/eLife.50414 |
Ejemplares similares
-
Polarization of Macrophages in Insects: Opening Gates for Immuno-Metabolic Research
por: Bajgar, Adam, et al.
Publicado: (2021) -
Macrophage‐derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection
por: Krejčová, Gabriela, et al.
Publicado: (2023) -
Coordinated Metabolic Transitions During Drosophila Embryogenesis and the Onset of Aerobic Glycolysis
por: Tennessen, Jason M., et al.
Publicado: (2014) -
On the origin of the functional versatility of macrophages
por: Bajgar, Adam, et al.
Publicado: (2023) -
SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst
por: Nguyen, Giang T, et al.
Publicado: (2020)