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Neuronal GPCR NPR-8 regulates C. elegans defense against pathogen infection

Increasing evidence indicates that infection-triggered host defenses are regulated by the nervous system. However, the precise mechanisms of this regulation are not well understood. Here, we demonstrate that neuronal G protein-coupled receptor NPR-8 negatively regulates Caenorhabditis elegans defens...

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Detalles Bibliográficos
Autores principales: Sellegounder, Durai, Liu, Yiyong, Wibisono, Phillip, Chen, Chia-Hui, Leap, David, Sun, Jingru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867885/
https://www.ncbi.nlm.nih.gov/pubmed/31799388
http://dx.doi.org/10.1126/sciadv.aaw4717