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Multidrug Resistance in Neisseria gonorrhoeae: Identification of Functionally Important Residues in the MtrD Efflux Protein

A key mechanism that Neisseria gonorrhoeae uses to achieve multidrug resistance is the expulsion of structurally different antimicrobials by the MtrD multidrug efflux protein. MtrD resembles the homologous Escherichia coli AcrB efflux protein with several common structural features, including an ope...

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Detalles Bibliográficos
Autores principales: Chitsaz, Mohsen, Booth, Lauren, Blyth, Mitchell T., O’Mara, Megan L., Brown, Melissa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867893/
https://www.ncbi.nlm.nih.gov/pubmed/31744915
http://dx.doi.org/10.1128/mBio.02277-19

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