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Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures

Human pluripotent stem cell (hPSC)-derived neurons provide exciting opportunities for in vitro modeling of neurological diseases and for advancing drug development and neurotoxicological studies. However, generating electrophysiologically mature neuronal networks from hPSCs has been challenging. Her...

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Detalles Bibliográficos
Autores principales:	Hyvärinen, Tanja, Hyysalo, Anu, Kapucu, Fikret Emre, Aarnos, Laura, Vinogradov, Andrey, Eglen, Stephen J., Ylä-Outinen, Laura, Narkilahti, Susanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868015/ https://www.ncbi.nlm.nih.gov/pubmed/31748598 http://dx.doi.org/10.1038/s41598-019-53647-8

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