Cargando…

Evans Blue Inhibits HBV Replication Through a Dual Antiviral Mechanism by Targeting Virus Binding and Capsid Assembly

Chronic hepatitis B (CHB) is a global health problem caused by human hepatitis B virus (HBV). Current treatment with interferons and nucleos(t)ide analogs (NAs) can cause population tolerance and drug resistance. Therefore, new antiviral drugs, especially those targeting host factors, are urgently n...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Yu, Liu, Chunlan, Tang, Wei, Zhang, Haiwei, Chen, Xulin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868041/ https://www.ncbi.nlm.nih.gov/pubmed/31798562 http://dx.doi.org/10.3389/fmicb.2019.02638

Ejemplares similares

Anthralin Suppresses the Proliferation of Influenza Virus by Inhibiting the Cap-Binding and Endonuclease Activity of Viral RNA Polymerase
por: Hu, Ao, et al.
Publicado: (2020)

DNA Encapsidation and Capsid Assembly Are Underexploited Antiviral Targets for the Treatment of Herpesviruses
por: Keil, Tara, et al.
Publicado: (2020)

Capsid Assembly Modulators as Antiviral Agents against HBV: Molecular Mechanisms and Clinical Perspectives
por: Taverniti, Valerio, et al.
Publicado: (2022)

Structure-Based Discovery of N-Sulfonylpiperidine-3-Carboxamides as Novel Capsid Assembly Modulators for Potent Inhibition of HBV Replication
por: Yang, Yang, et al.
Publicado: (2022)

Antiviral Activity and Pharmacokinetics of the Hepatitis B Virus (HBV) Capsid Assembly Modulator GLS4 in Patients With Chronic HBV Infection
por: Zhang, Hong, et al.
Publicado: (2020)

The HBV Core Protein and Core Particle Both Bind to the PPiase Par14 and Par17 to Enhance Their Stabilities and HBV Replication
por: Saeed, Umar, et al.
Publicado: (2021)

Decrease of Clone Diversity in IgM Repertoires of HBV Chronically Infected Individuals With High Level of Viral Replication
por: Hong, Binbin, et al.
Publicado: (2021)

Evans Blue Reduces Neuropathic Pain Behavior by Inhibiting Spinal ATP Release
por: Yin, Yuhua, et al.
Publicado: (2019)

The Dual Role of an ESCRT-0 Component HGS in HBV Transcription and Naked Capsid Secretion
por: Chou, Shu-Fan, et al.
Publicado: (2015)

“Albumin Hitchhiking” with an Evans Blue Analog for Cancer Theranostics
por: Ehlerding, Emily B., et al.
Publicado: (2018)

The Determination of the Blood Volume in Man with Evans Blue ("T-1824")
por: Davis, L. J.
Publicado: (1942)

SIRT2 Promotes HBV Transcription and Replication by Targeting Transcription Factor p53 to Increase the Activities of HBV Enhancers and Promoters
por: Wu, Dai-Qing, et al.
Publicado: (2022)

Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein
por: Vozzolo, Luciano, et al.
Publicado: (2010)

Optimization of Evans blue quantitation in limited rat tissue samples
por: Wang, Hwai-Lee, et al.
Publicado: (2014)

Evans Blue Dye: A Revisit of Its Applications in Biomedicine
por: Yao, Linpeng, et al.
Publicado: (2018)

The dual functions of KDM7A in HBV replication and immune microenvironment
por: Yang, Di, et al.
Publicado: (2023)

Pimobendan Inhibits HBV Transcription and Replication by Suppressing HBV Promoters Activity
por: Yuan, Si-Yu, et al.
Publicado: (2022)

Dengue Virus Capsid Interacts with DDX3X–A Potential Mechanism for Suppression of Antiviral Functions in Dengue Infection
por: Kumar, Rinki, et al.
Publicado: (2018)

Targeting the HIV-1 and HBV Capsids, an EnCore
por: McFadden, William M., et al.
Publicado: (2023)

Antiviral Immunotoxin Against Bovine herpesvirus-1: Targeted Inhibition of Viral Replication and Apoptosis of Infected Cell
por: Xu, Jian, et al.
Publicado: (2018)

Chemical Conjugation of Evans Blue Derivative: A Strategy to Develop Long-Acting Therapeutics through Albumin Binding
por: Chen, Haojun, et al.
Publicado: (2016)

Distinct Patterns of Cerebral Extravasation by Evans Blue and Sodium Fluorescein in Rats
por: Yen, Lola Fenghuei, et al.
Publicado: (2013)

Analysis of Zebrafish Larvae Skeletal Muscle Integrity with Evans Blue Dye
por: Smith, Sarah J., et al.
Publicado: (2015)

Injection of Evans blue dye to fluorescently label and image intact vasculature
por: Honeycutt, Samuel E, et al.
Publicado: (2020)

Corrigendum to “Evans Blue Dye: A Revisit of Its Applications in Biomedicine”
por: Yao, Linpeng, et al.
Publicado: (2021)

Dr. Evan Gabriel Evans
Publicado: (1916)

Kaposi's Sarcoma-Associated Herpesvirus ORF6 Gene Is Essential in Viral Lytic Replication
por: Peng, Can, et al.
Publicado: (2014)

Inhibition of Arenavirus Entry and Replication by the Cell-Intrinsic Restriction Factor ZMPSTE24 Is Enhanced by IFITM Antiviral Activity
por: Stott-Marshall, Robert J., et al.
Publicado: (2022)

Design and Synthesis of Hepatitis B Virus (HBV) Capsid Assembly Modulators and Evaluation of Their Activity in Mammalian Cell Model
por: Spunde, Karina, et al.
Publicado: (2022)

Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication
por: Gruenke, Paige R, et al.
Publicado: (2022)

Pharmacomodulation of a ligand targeting the HBV capsid hydrophobic pocket
por: Briday, Mathilde, et al.
Publicado: (2022)

A Broad-Spectrum Antiviral Molecule, Protoporphyrin IX, Acts as a Moderator of HIV-1 Capsid Assembly by Targeting the Capsid Hexamer
por: Zhang, Da-Wei, et al.
Publicado: (2022)

The Origin of Capsid-Derived Immune Complexes and Their Impact on HBV-Induced Liver Diseases
por: Zhang, Xiaonan, et al.
Publicado: (2022)

Simultaneously inhibition of HIV and HBV replication through a dual small interfering RNA expression system
por: Wu, Kailang, et al.
Publicado: (2007)

Inhibition of Hepatitis B Virus (HBV) replication and antigen expression by Brucea javanica (L.) Merr. oil emulsion
por: Qin, Bo, et al.
Publicado: (2023)

Evans Blue Attachment Enhances Somatostatin Receptor Subtype-2 Imaging and Radiotherapy
por: Tian, Rui, et al.
Publicado: (2018)

Sustained Inhibition of HBV Replication In Vivo after Systemic Injection of AAVs Encoding Artificial Antiviral Primary MicroRNAs
por: Maepa, Mohube Betty, et al.
Publicado: (2017)

Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes
por: Lucifora, Julie, et al.
Publicado: (2018)

Establishment of stable cell lines in which the HBV genome replicates episomally for evaluation of antivirals
por: Sun, Suofeng, et al.
Publicado: (2018)

A Comparison of Evans Blue and 4-(p-Iodophenyl)butyryl Albumin Binding Moieties on an Integrin α(v)β(6) Binding Peptide
por: Davis, Ryan A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6gikhorefmfdnh2f3joajn451r