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Molecular Analysis of Goodpasture’s Disease Following Hematopoietic Stem Cell Transplant in a Pediatric Patient, Recalls the Conformeropathy of Wild-Type Anti-GBM Disease

Background: Goodpasture's disease (GP) is mediated by autoantibodies that bind the glomerular and alveolar basement membrane, causing rapidly progressive glomerulonephritis with or without pulmonary hemorrhage. The autoantibodies bind neoepitopes formed upon disruption of the quaternary structu...

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Detalles Bibliográficos
Autores principales: Gray, Paul E., McCarthy, Hugh, Siggs, Owen M., Saleem, Moin A., O' Brien, Tracy, Frith, Katie, Ziegler, John B., Kitching, A. Richard, Fogo, Agnes B., Hudson, Billy G., Pedchenko, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868084/
https://www.ncbi.nlm.nih.gov/pubmed/31798588
http://dx.doi.org/10.3389/fimmu.2019.02659

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