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Molecular Analysis of Goodpasture’s Disease Following Hematopoietic Stem Cell Transplant in a Pediatric Patient, Recalls the Conformeropathy of Wild-Type Anti-GBM Disease
Background: Goodpasture's disease (GP) is mediated by autoantibodies that bind the glomerular and alveolar basement membrane, causing rapidly progressive glomerulonephritis with or without pulmonary hemorrhage. The autoantibodies bind neoepitopes formed upon disruption of the quaternary structu...
Autores principales: | Gray, Paul E., McCarthy, Hugh, Siggs, Owen M., Saleem, Moin A., O' Brien, Tracy, Frith, Katie, Ziegler, John B., Kitching, A. Richard, Fogo, Agnes B., Hudson, Billy G., Pedchenko, Vadim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868084/ https://www.ncbi.nlm.nih.gov/pubmed/31798588 http://dx.doi.org/10.3389/fimmu.2019.02659 |
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