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Hyperexcitability and impaired intracortical inhibition in patients with fragile-X syndrome

Fragile-X syndrome (FXS) is characterized by neurological and psychiatric problems symptomatic of cortical hyperexcitability. Recent animal studies identified deficient γ-aminobutyricacid (GABA) inhibition as a key mechanism for hyperexcitability in FXS, but the GABA system remains largely unexplore...

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Detalles Bibliográficos
Autores principales: Morin-Parent, Florence, Champigny, Camille, Lacroix, Angelina, Corbin, François, Lepage, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868148/
https://www.ncbi.nlm.nih.gov/pubmed/31748507
http://dx.doi.org/10.1038/s41398-019-0650-z