Cargando…

Hyperexcitability and impaired intracortical inhibition in patients with fragile-X syndrome

Fragile-X syndrome (FXS) is characterized by neurological and psychiatric problems symptomatic of cortical hyperexcitability. Recent animal studies identified deficient γ-aminobutyricacid (GABA) inhibition as a key mechanism for hyperexcitability in FXS, but the GABA system remains largely unexplore...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morin-Parent, Florence, Champigny, Camille, Lacroix, Angelina, Corbin, François, Lepage, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868148/ https://www.ncbi.nlm.nih.gov/pubmed/31748507 http://dx.doi.org/10.1038/s41398-019-0650-z

Ejemplares similares

Combining Lovastatin and Minocycline for the Treatment of Fragile X Syndrome: Results From the LovaMiX Clinical Trial
por: Champigny, Camille, et al.
Publicado: (2022)

Hyperexcitability and Homeostasis in Fragile X Syndrome
por: Liu, Xiaopeng, et al.
Publicado: (2022)

Clinical significance of matrix metalloproteinase-9 in Fragile X Syndrome
por: Laroui, Asma, et al.
Publicado: (2022)

Mechanisms Driving the Emergence of Neuronal Hyperexcitability in Fragile X Syndrome
por: Bülow, Pernille, et al.
Publicado: (2022)

APP Causes Hyperexcitability in Fragile X Mice
por: Westmark, Cara J., et al.
Publicado: (2016)

An “Omic” Overview of Fragile X Syndrome
por: Dionne, Olivier, et al.
Publicado: (2021)

Hyperexcitability of Sensory Neurons in Fragile X Mouse Model
por: Deng, Pan-Yue, et al.
Publicado: (2021)

Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome
por: Pedapati, Ernest V., et al.
Publicado: (2022)

Alteration of Fatty Acid Profile in Fragile X Syndrome
por: Abolghasemi, Armita, et al.
Publicado: (2022)

A resting EEG study of neocortical hyperexcitability and altered functional connectivity in fragile X syndrome
por: Wang, Jun, et al.
Publicado: (2017)

New insights of altered lipid profile in Fragile X Syndrome
por: Çaku, Artuela, et al.
Publicado: (2017)

Impaired intracortical inhibition demonstrated in vivo in people with Dravet syndrome
por: Stern, William M., et al.
Publicado: (2017)

Rates of protein synthesis are reduced in peripheral blood mononuclear cells (PBMCs) from fragile X individuals
por: Dionne, Olivier, et al.
Publicado: (2021)

Association of lipid rafts cholesterol with clinical profile in fragile X syndrome
por: Toupin, Amanda, et al.
Publicado: (2022)

Superior non-specific motor learning in the blind
por: Morin-Parent, Florence, et al.
Publicado: (2017)

A new strategy to uncover fragile X proteomic biomarkers using the nascent proteome of peripheral blood mononuclear cells (PBMCs)
por: Dionne, Olivier, et al.
Publicado: (2021)

Impaired Functional Connectivity Underlies Fragile X Syndrome
por: Gildin, Lital, et al.
Publicado: (2022)

Fragile X syndrome and fragile X-associated disorders
por: Rajaratnam, Akash, et al.
Publicado: (2017)

Fragile X Syndrome
por: McLennan, Yingratana, et al.
Publicado: (2011)

Fragile X Syndrome
por: Saldarriaga, Wilmar, et al.
Publicado: (2014)

Impaired GABA Neural Circuits Are Critical for Fragile X Syndrome
por: Gao, Fei, et al.
Publicado: (2018)

Impaired Attention Orienting in Young Children With Fragile X Syndrome
por: Chernenok, Mariya, et al.
Publicado: (2019)

Static magnetic stimulation of the primary motor cortex impairs online but not offline motor sequence learning
por: Lacroix, Angélina, et al.
Publicado: (2019)

Impairment of Procedural Learning and Motor Intracortical Inhibition in Neurofibromatosis Type 1 Patients
por: Zimerman, Máximo, et al.
Publicado: (2015)

Excess protein synthesis in Drosophila Fragile X mutants impairs long-term memory
por: Bolduc, François V., et al.
Publicado: (2008)

Reduced Lateral Inhibition Impairs Olfactory Computations and Behaviors in a Drosophila Model of Fragile X Syndrome
por: Franco, Luis M., et al.
Publicado: (2017)

Short Intracortical Inhibition During Voluntary Movement Reveals Persistent Impairment Post-stroke
por: Ding, Qian, et al.
Publicado: (2019)

Aging in fragile X syndrome
por: Utari, Agustini, et al.
Publicado: (2010)

Fragile X Syndrome in children
por: Acero-Garcés, David O., et al.
Publicado: (2023)

Repeatability of long intracortical inhibition in healthy subjects
por: de Goede, Annika A., et al.
Publicado: (2016)

Intracortical Inhibition in the Affected Hemisphere in Limb Amputation
por: Candido Santos, Ludmilla, et al.
Publicado: (2020)

Visual Behavior Impairments as an Aberrant Sensory Processing in the Mouse Model of Fragile X Syndrome
por: Felgerolle, Chloé, et al.
Publicado: (2019)

Behavioral inflexibility in fragile X syndrome: Accounts from caregivers and self-advocates
por: Jones, Angelina, et al.
Publicado: (2023)

Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome
por: Berman, Robert F, et al.
Publicado: (2014)

Stress Odorant Sensory Response Dysfunction in Drosophila Fragile X Syndrome Mutants
por: Androschuk, Alaura, et al.
Publicado: (2018)

Targeted treatments for fragile X syndrome
por: Berry-Kravis, Elizabeth, et al.
Publicado: (2011)

Pathological Plasticity in Fragile X Syndrome
por: Martin, Brandon S., et al.
Publicado: (2012)

Auditory Processing in Fragile X Syndrome
por: Rotschafer, Sarah E., et al.
Publicado: (2014)

Modeling Fragile X Syndrome in Drosophila
por: Drozd, Małgorzata, et al.
Publicado: (2018)

Molecular Biomarkers in Fragile X Syndrome
por: Zafarullah, Marwa, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ev3kpv741frsn88m2sddirr474