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An umpolung strategy to react catalytic enols with nucleophiles

The selective synthesis of α-functionalized ketones with two similar enolizable positions can be accomplished using allylic alcohols and iridium(III) catalysts. A formal 1,3-hydrogen shift on allylic alcohols generates catalytic iridium-enolates in a stereospecific manner, which are able to react wi...

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Detalles Bibliográficos
Autores principales: Sanz-Marco, Amparo, Martinez-Erro, Samuel, Pauze, Martin, Gómez-Bengoa, Enrique, Martín-Matute, Belén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868166/
https://www.ncbi.nlm.nih.gov/pubmed/31748504
http://dx.doi.org/10.1038/s41467-019-13175-5

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