Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5

Chronic pain is a complex trait that is moderately heritable and genetically, as well as phenotypically, correlated with major depressive disorder (MDD). Use of the conditional false discovery rate (cFDR) approach, which leverages pleiotropy identified from existing GWAS outputs, has been successful...

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Detalles Bibliográficos
Autores principales: Johnston, Keira J. A., Adams, Mark J., Nicholl, Barbara I., Ward, Joey, Strawbridge, Rona J., McIntosh, Andrew M., Smith, Daniel J., Bailey, Mark E. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868167/
https://www.ncbi.nlm.nih.gov/pubmed/31748543
http://dx.doi.org/10.1038/s41398-019-0613-4

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