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Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis
The pregnane X receptor (PXR) is a nuclear receptor (NR), involved in the detoxification of xenobiotic compounds. Recently, its presence was reported in the human vasculature and its ligands were proposed to exhibit anti-atherosclerotic effects. Since platelets contribute towards the development of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868193/ https://www.ncbi.nlm.nih.gov/pubmed/31748641 http://dx.doi.org/10.1038/s41598-019-53218-x |