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Structural determinants of microtubule minus end preference in CAMSAP CKK domains

CAMSAP/Patronins regulate microtubule minus-end dynamics. Their end specificity is mediated by their CKK domains, which we proposed recognise specific tubulin conformations found at minus ends. To critically test this idea, we compared the human CAMSAP1 CKK domain (HsCKK) with a CKK domain from Naeg...

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Detalles Bibliográficos
Autores principales: Atherton, Joseph, Luo, Yanzhang, Xiang, Shengqi, Yang, Chao, Rai, Ankit, Jiang, Kai, Stangier, Marcel, Vemu, Annapurna, Cook, Alexander D., Wang, Su, Roll-Mecak, Antonina, Steinmetz, Michel O., Akhmanova, Anna, Baldus, Marc, Moores, Carolyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868217/
https://www.ncbi.nlm.nih.gov/pubmed/31748546
http://dx.doi.org/10.1038/s41467-019-13247-6