Cargando…

VGLL4 interacts with STAT3 to function as a tumor suppressor in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is an aggressive malignancy with a poor prognosis, and there are no effective molecular-targeted drugs for TNBC patients in clinical practice. The JAK-STAT pathway is implicated in tumorigenesis and the progression of various cancers. In this study, the results d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Hongming, Luo, Qifeng, Deng, Xiaochong, Ji, Changle, Li, Dengfeng, Munankarmy, Amik, Jian, Wei, Zhao, Junyong, Fang, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868227/ https://www.ncbi.nlm.nih.gov/pubmed/31748508 http://dx.doi.org/10.1038/s12276-019-0338-8

Ejemplares similares

MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor
por: Deng, Xiaochong, et al.
Publicado: (2021)

MicroRNA-301b promotes cell proliferation and apoptosis resistance in triple-negative breast cancer by targeting CYLD
por: Song, Hongming, et al.
Publicado: (2018)

A Triple-Regulated Oncolytic Adenovirus Carrying MicroRNA-143 Exhibits Potent Antitumor Efficacy in Colorectal Cancer
por: Luo, Qifeng, et al.
Publicado: (2020)

Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer
por: Hua, Kaiyao, et al.
Publicado: (2020)

Circular RNA_0006014 promotes breast cancer progression through sponging miR-885-3p to regulate NTRK2 and PIK3/AKT pathway
por: Zhou, Xiqian, et al.
Publicado: (2022)

Hsa_circ_0053063 inhibits breast cancer cell proliferation via hsa_circ_0053063/hsa-miR-330-3p/PDCD4 axis
por: Ji, Changle, et al.
Publicado: (2021)

The Role of miR-640: A Potential Suppressor in Breast Cancer via Wnt7b/β-catenin Signaling Pathway
por: Tang, Chun, et al.
Publicado: (2021)

Serotonin and YAP/VGLL4 Balance Correlated with Progression and Poor Prognosis of Hepatocellular Carcinoma
por: Shu, Bo, et al.
Publicado: (2018)

Circular RNA circRPPH1 promotes breast cancer progression via circRPPH1-miR-512-5p-STAT1 axis
por: Huang, Yixiang, et al.
Publicado: (2021)

Hybrid Schwannoma-Perineurioma Frequently Harbors VGLL3 Rearrangement
por: Dickson, Brendan C., et al.
Publicado: (2021)

VGLL4 plays a critical role in heart valve development and homeostasis
por: Yu, Wei, et al.
Publicado: (2019)

A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors
por: Mesrouze, Yannick, et al.
Publicado: (2020)

VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis
por: Watson, Sarah, et al.
Publicado: (2023)

Negative regulators of STAT3 signaling pathway in cancers
por: Wu, Moli, et al.
Publicado: (2019)

Genome-wide Interaction Study Implicates VGLL2 and Alcohol Exposure and PRL and Smoking in Orofacial Cleft Risk
por: Carlson, Jenna C., et al.
Publicado: (2022)

Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development
por: Sheldon, Caroline, et al.
Publicado: (2022)

Disruption of STAT3-DNMT1 interaction by SH-I-14 induces re-expression of tumor suppressor genes and inhibits growth of triple-negative breast tumor
por: Kang, Hyo Jin, et al.
Publicado: (2015)

VGLL3-regulated gene network as a promoter of sex biased autoimmune diseases
por: Liang, Yun, et al.
Publicado: (2016)

VGLL4 promotes osteoblast differentiation by antagonizing TEADs-inhibited Runx2 transcription
por: Suo, Jinlong, et al.
Publicado: (2020)

Linking vgll3 genotype and aggressive behaviour in juvenile Atlantic salmon (Salmo salar)
por: Bangura, Paul Bai, et al.
Publicado: (2022)

VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer
por: Zhang, Yinglong, et al.
Publicado: (2017)

Development of supermale and all-male Atlantic salmon to research the vgll3 allele - puberty link
por: Fjelldal, Per Gunnar, et al.
Publicado: (2020)

VGLL4 and MENIN function as TEAD1 corepressors to block pancreatic β cell proliferation
por: Li, Feng, et al.
Publicado: (2023)

YAP–VGLL4 antagonism defines the major physiological function of the Hippo signaling effector YAP
por: Cai, Jing, et al.
Publicado: (2022)

VGLL3 expression is associated with macrophage infiltration and predicts poor prognosis in epithelial ovarian cancer
por: Haque, Razaul, et al.
Publicado: (2023)

Tumor-Derived circRNAs as Circulating Biomarkers for Breast Cancer
por: Yu, Yunhe, et al.
Publicado: (2022)

The influence of vgll3 genotypes on sea age at maturity is altered in farmed mowi strain Atlantic salmon
por: Ayllon, Fernando, et al.
Publicado: (2019)

TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in zebrafish
por: Fillatre, Jonathan, et al.
Publicado: (2019)

VGLL3 is a prognostic biomarker and correlated with clinical pathologic features and immune infiltrates in stomach adenocarcinoma
por: Zhang, Lihua, et al.
Publicado: (2020)

Deficiency of Vgll2 Gene Alters the Gene Expression Profiling of Skeletal Muscle Subjected to Mechanical Overload
por: Hitachi, Keisuke, et al.
Publicado: (2019)

VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid–liquid phase separation
por: Horii, Yuma, et al.
Publicado: (2023)

Genomic regulation of invasion by STAT3 in triple negative breast cancer
por: McDaniel, Joy M., et al.
Publicado: (2016)

Tumor suppressor role of microRNA-1296 in triple-negative breast cancer
por: Phan, Binh, et al.
Publicado: (2016)

Progress in the research of p53 tumour suppressor activity controlled by Numb in triple‐negative breast cancer
por: Xian, Jie, et al.
Publicado: (2020)

The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon (Salmo salar L.) Males
por: Ayllon, Fernando, et al.
Publicado: (2015)

Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis
por: Kjærner-Semb, Erik, et al.
Publicado: (2018)

VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle
por: Figeac, Nicolas, et al.
Publicado: (2019)

Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway
por: Wang, Xuehui, et al.
Publicado: (2021)

Correction to: Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway
por: Wang, Xuehui, et al.
Publicado: (2021)

56371 The Signaling Axis of Tumor Suppressor LKB1 in Triple Negative Breast Cancer
por: Nguyen, Khoa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qsgv1cnj4l5djf9mgshs9sen8q