Intravitreal injection of adenosine A(2A) receptor antagonist reduces neuroinflammation, vascular leakage and cell death in the retina of diabetic mice

Diabetic retinopathy is a major complication of diabetes mellitus and a leading cause of blindness. The pathogenesis of diabetic retinopathy is accompanied by chronic low-grade inflammation. Evidence shows that the blockade of adenosine A(2A) receptors (A(2A)R) affords protection to the retina throu...

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Detalles Bibliográficos
Autores principales: Aires, Inês Dinis, Madeira, Maria Helena, Boia, Raquel, Rodrigues-Neves, Ana Catarina, Martins, Joana Margarida, Ambrósio, António Francisco, Santiago, Ana Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868354/
https://www.ncbi.nlm.nih.gov/pubmed/31748653
http://dx.doi.org/10.1038/s41598-019-53627-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868354/
https://www.ncbi.nlm.nih.gov/pubmed/31748653
http://dx.doi.org/10.1038/s41598-019-53627-y

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