Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage

The addition of poly(ADP-ribose) (PAR) chains along the chromatin fiber due to PARP1 activity regulates the recruitment of multiple factors to sites of DNA damage. In this manuscript, we investigated how, besides direct binding to PAR, early chromatin unfolding events controlled by PAR signaling con...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Rebecca, Lebeaupin, Théo, Juhász, Szilvia, Chapuis, Catherine, D’Augustin, Ostiane, Dutertre, Stéphanie, Burkovics, Peter, Biertümpfel, Christian, Timinszky, Gyula, Huet, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868358/
https://www.ncbi.nlm.nih.gov/pubmed/31566235
http://dx.doi.org/10.1093/nar/gkz820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868358/
https://www.ncbi.nlm.nih.gov/pubmed/31566235
http://dx.doi.org/10.1093/nar/gkz820

Ejemplares similares