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Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage
The addition of poly(ADP-ribose) (PAR) chains along the chromatin fiber due to PARP1 activity regulates the recruitment of multiple factors to sites of DNA damage. In this manuscript, we investigated how, besides direct binding to PAR, early chromatin unfolding events controlled by PAR signaling con...
Autores principales: | Smith, Rebecca, Lebeaupin, Théo, Juhász, Szilvia, Chapuis, Catherine, D’Augustin, Ostiane, Dutertre, Stéphanie, Burkovics, Peter, Biertümpfel, Christian, Timinszky, Gyula, Huet, Sébastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868358/ https://www.ncbi.nlm.nih.gov/pubmed/31566235 http://dx.doi.org/10.1093/nar/gkz820 |
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