A novel mode of DnaA–DnaA interaction promotes ADP dissociation for reactivation of replication initiation activity

ATP-DnaA is temporally increased to initiate replication during the cell cycle. Two chromosomal loci, DARS (DnaA-reactivating sequences) 1 and 2, promote ATP-DnaA production by nucleotide exchange of ADP-DnaA for timely initiation. ADP-DnaA complexes are constructed on DARS1 and DARS2, bearing a clu...

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Detalles Bibliográficos
Autores principales: Sugiyama, Ryo, Kasho, Kazutoshi, Miyoshi, Kenya, Ozaki, Shogo, Kagawa, Wataru, Kurumizaka, Hitoshi, Katayama, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868365/
https://www.ncbi.nlm.nih.gov/pubmed/31535134
http://dx.doi.org/10.1093/nar/gkz795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868365/
https://www.ncbi.nlm.nih.gov/pubmed/31535134
http://dx.doi.org/10.1093/nar/gkz795

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