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Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases
The widespread occurrence of repetitive stretches of DNA in genomes of organisms across the tree of life imposes fundamental challenges for sequencing, genome assembly, and automated annotation of genes and proteins. This multi-level problem can lead to errors in genome and protein databases that ar...
Autores principales: | Tørresen, Ole K, Star, Bastiaan, Mier, Pablo, Andrade-Navarro, Miguel A, Bateman, Alex, Jarnot, Patryk, Gruca, Aleksandra, Grynberg, Marcin, Kajava, Andrey V, Promponas, Vasilis J, Anisimova, Maria, Jakobsen, Kjetill S, Linke, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868369/ https://www.ncbi.nlm.nih.gov/pubmed/31584084 http://dx.doi.org/10.1093/nar/gkz841 |
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