UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity

Accurate DNA replication is critical for the maintenance of genome integrity and cellular survival. Cancer-associated alterations often involve key players of DNA replication and of the DNA damage-signalling cascade. Post-translational modifications play a fundamental role in coordinating replicatio...

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Detalles Bibliográficos
Autores principales: Cipolla, Lina, Bertoletti, Federica, Maffia, Antonio, Liang, Chih-Chao, Lehmann, Alan R, Cohn, Martin A, Sabbioneda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868395/
https://www.ncbi.nlm.nih.gov/pubmed/31586398
http://dx.doi.org/10.1093/nar/gkz824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868395/
https://www.ncbi.nlm.nih.gov/pubmed/31586398
http://dx.doi.org/10.1093/nar/gkz824

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