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Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam

BACKGROUND: The Mekong Delta of Vietnam is a hotspot of antimicrobial use (AMU), but there is no information on the quality of the labelling and strength of antimicrobial products used in poultry production. METHODS: Based on a large random sample of farms, we identified the 20 most used antimicrobi...

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Autores principales: Yen, Nguyen Thi Phuong, Phu, Doan Hoang, Van Cuong, Nguyen, Kiet, Bach Tuan, Hien, Be Vo, Padungtod, Pawin, Truong, Dinh Bao, Thwaites, Guy E., Carrique‐Mas, Juan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868449/
https://www.ncbi.nlm.nih.gov/pubmed/31373776
http://dx.doi.org/10.1002/vms3.189
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author Yen, Nguyen Thi Phuong
Phu, Doan Hoang
Van Cuong, Nguyen
Kiet, Bach Tuan
Hien, Be Vo
Padungtod, Pawin
Truong, Dinh Bao
Thwaites, Guy E.
Carrique‐Mas, Juan J.
author_facet Yen, Nguyen Thi Phuong
Phu, Doan Hoang
Van Cuong, Nguyen
Kiet, Bach Tuan
Hien, Be Vo
Padungtod, Pawin
Truong, Dinh Bao
Thwaites, Guy E.
Carrique‐Mas, Juan J.
author_sort Yen, Nguyen Thi Phuong
collection PubMed
description BACKGROUND: The Mekong Delta of Vietnam is a hotspot of antimicrobial use (AMU), but there is no information on the quality of the labelling and strength of antimicrobial products used in poultry production. METHODS: Based on a large random sample of farms, we identified the 20 most used antimicrobial products in the area, and investigated their antimicrobial active ingredient (AAI) content by UPLC‐MS/MS (91 analytical tests). RESULTS: Only 17/59 (28.8%) batches contained all AAIs within 10% of the declared strength. Worryingly, 65.0% products provided in their label preparation guidelines for both therapeutic and prophylactic use. Withdrawal times for both meat and eggs were stated in 8/20 (40%) products. CONCLUSION: Results highlight deficiencies in quality and labelling contents that undermine authorities’ efforts to discourage inappropriate use of antimicrobials.
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spelling pubmed-68684492019-11-25 Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam Yen, Nguyen Thi Phuong Phu, Doan Hoang Van Cuong, Nguyen Kiet, Bach Tuan Hien, Be Vo Padungtod, Pawin Truong, Dinh Bao Thwaites, Guy E. Carrique‐Mas, Juan J. Vet Med Sci Original Articles BACKGROUND: The Mekong Delta of Vietnam is a hotspot of antimicrobial use (AMU), but there is no information on the quality of the labelling and strength of antimicrobial products used in poultry production. METHODS: Based on a large random sample of farms, we identified the 20 most used antimicrobial products in the area, and investigated their antimicrobial active ingredient (AAI) content by UPLC‐MS/MS (91 analytical tests). RESULTS: Only 17/59 (28.8%) batches contained all AAIs within 10% of the declared strength. Worryingly, 65.0% products provided in their label preparation guidelines for both therapeutic and prophylactic use. Withdrawal times for both meat and eggs were stated in 8/20 (40%) products. CONCLUSION: Results highlight deficiencies in quality and labelling contents that undermine authorities’ efforts to discourage inappropriate use of antimicrobials. John Wiley and Sons Inc. 2019-08-02 /pmc/articles/PMC6868449/ /pubmed/31373776 http://dx.doi.org/10.1002/vms3.189 Text en © 2019 The Authors. Veterinary Medicine and Science Published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Yen, Nguyen Thi Phuong
Phu, Doan Hoang
Van Cuong, Nguyen
Kiet, Bach Tuan
Hien, Be Vo
Padungtod, Pawin
Truong, Dinh Bao
Thwaites, Guy E.
Carrique‐Mas, Juan J.
Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam
title Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam
title_full Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam
title_fullStr Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam
title_full_unstemmed Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam
title_short Labelling and quality of antimicrobial products used in chicken flocks in the Mekong Delta of Vietnam
title_sort labelling and quality of antimicrobial products used in chicken flocks in the mekong delta of vietnam
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868449/
https://www.ncbi.nlm.nih.gov/pubmed/31373776
http://dx.doi.org/10.1002/vms3.189
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