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Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study

Epigenetic changes may contribute substantially to risks of diseases of aging. Previous studies reported seven methylation variable positions (MVPs) robustly associated with incident type 2 diabetes mellitus (T2DM). However, their causal roles in T2DM are unclear. In an incident T2DM case-cohort stu...

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Detalles Bibliográficos
Autores principales: Cardona, Alexia, Day, Felix R., Perry, John R.B., Loh, Marie, Chu, Audrey Y., Lehne, Benjamin, Paul, Dirk S., Lotta, Luca A., Stewart, Isobel D., Kerrison, Nicola D., Scott, Robert A., Khaw, Kay-Tee, Forouhi, Nita G., Langenberg, Claudia, Liu, Chunyu, Mendelson, Michael M., Levy, Daniel, Beck, Stephan, Leslie, R. David, Dupuis, Josée, Meigs, James B., Kooner, Jaspal S., Pihlajamäki, Jussi, Vaag, Allan, Perfilyev, Alexander, Ling, Charlotte, Hivert, Marie-France, Chambers, John C., Wareham, Nicholas J., Ong, Ken K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868468/
https://www.ncbi.nlm.nih.gov/pubmed/31506343
http://dx.doi.org/10.2337/db18-0290

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