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Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study
Epigenetic changes may contribute substantially to risks of diseases of aging. Previous studies reported seven methylation variable positions (MVPs) robustly associated with incident type 2 diabetes mellitus (T2DM). However, their causal roles in T2DM are unclear. In an incident T2DM case-cohort stu...
Autores principales: | Cardona, Alexia, Day, Felix R., Perry, John R.B., Loh, Marie, Chu, Audrey Y., Lehne, Benjamin, Paul, Dirk S., Lotta, Luca A., Stewart, Isobel D., Kerrison, Nicola D., Scott, Robert A., Khaw, Kay-Tee, Forouhi, Nita G., Langenberg, Claudia, Liu, Chunyu, Mendelson, Michael M., Levy, Daniel, Beck, Stephan, Leslie, R. David, Dupuis, Josée, Meigs, James B., Kooner, Jaspal S., Pihlajamäki, Jussi, Vaag, Allan, Perfilyev, Alexander, Ling, Charlotte, Hivert, Marie-France, Chambers, John C., Wareham, Nicholas J., Ong, Ken K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868468/ https://www.ncbi.nlm.nih.gov/pubmed/31506343 http://dx.doi.org/10.2337/db18-0290 |
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