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Pharmacological plasticity—How do you hit a moving target?

Paul Ehrlich's concept of the magic bullet, by which a single drug induces pharmacological effects by interacting with a single receptor has been a strong driving force in pharmacology for a century. It is continually thwarted, though, by the fact that the treated organism is highly dynamic and...

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Detalles Bibliográficos
Autores principales: Parnham, Michael J., Geisslinger, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868654/
https://www.ncbi.nlm.nih.gov/pubmed/31768257
http://dx.doi.org/10.1002/prp2.532

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