Cargando…
Pharmacological plasticity—How do you hit a moving target?
Paul Ehrlich's concept of the magic bullet, by which a single drug induces pharmacological effects by interacting with a single receptor has been a strong driving force in pharmacology for a century. It is continually thwarted, though, by the fact that the treated organism is highly dynamic and...
Autores principales: | Parnham, Michael J., Geisslinger, Gerd |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868654/ https://www.ncbi.nlm.nih.gov/pubmed/31768257 http://dx.doi.org/10.1002/prp2.532 |
Ejemplares similares
-
Cellular Plasticity and Tumor Microenvironment in Gliomas: The Struggle to Hit a Moving Target
por: Gargini, Ricardo, et al.
Publicado: (2020) -
Hitting the right target: taxonomic challenges for, and of, plant invasions
por: Pyšek, Petr, et al.
Publicado: (2013) -
How γ-secretase hits a moving target
por: Sanders, Charles R
Publicado: (2016) -
The HIV‐1 envelope glycoprotein structure: nailing down a moving target
por: Ward, Andrew B, et al.
Publicado: (2017) -
Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections
por: Sies, Helmut, et al.
Publicado: (2020)