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Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients

BACKGROUND: Adjuvanticity, which is the ability of neoplastic cells to deliver danger signals, is critical for the host immune system to mount spontaneous and therapy-driven anticancer immune responses. One of such signals, i.e., the exposure of calreticulin (CALR) on the membrane of malignant cells...

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Detalles Bibliográficos
Autores principales: Kasikova, Lenka, Hensler, Michal, Truxova, Iva, Skapa, Petr, Laco, Jan, Belicova, Lucie, Praznovec, Ivan, Vosahlikova, Sarka, Halaska, Michael J., Brtnicky, Tomas, Rob, Lukas, Presl, Jiri, Kostun, Jan, Cremer, Isabelle, Ryska, Ales, Kroemer, Guido, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868694/
https://www.ncbi.nlm.nih.gov/pubmed/31747968
http://dx.doi.org/10.1186/s40425-019-0781-z

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