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Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients
BACKGROUND: Adjuvanticity, which is the ability of neoplastic cells to deliver danger signals, is critical for the host immune system to mount spontaneous and therapy-driven anticancer immune responses. One of such signals, i.e., the exposure of calreticulin (CALR) on the membrane of malignant cells...
Autores principales: | Kasikova, Lenka, Hensler, Michal, Truxova, Iva, Skapa, Petr, Laco, Jan, Belicova, Lucie, Praznovec, Ivan, Vosahlikova, Sarka, Halaska, Michael J., Brtnicky, Tomas, Rob, Lukas, Presl, Jiri, Kostun, Jan, Cremer, Isabelle, Ryska, Ales, Kroemer, Guido, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868694/ https://www.ncbi.nlm.nih.gov/pubmed/31747968 http://dx.doi.org/10.1186/s40425-019-0781-z |
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