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Recombinant human milk fat globule-EGF factor VIII (rhMFG-E8) as a therapy for sepsis after acute exposure to alcohol

BACKGROUND: Alcohol intake predisposes to infections and sepsis. Alcohol and sepsis inhibit the expression of milk fat globule epidermal growth factor-factor VIII (MFG-E8), a glycoprotein essential for optimal efferocytosis, resulting in the release of proinflammatory molecules and increased sepsis...

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Detalles Bibliográficos
Autores principales:	Chaung, Wayne W., Brenner, Max, Yen, Hao-Ting, Ochani, Mahendar L., Jacob, Asha, Wang, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868720/ https://www.ncbi.nlm.nih.gov/pubmed/31747882 http://dx.doi.org/10.1186/s10020-019-0118-x

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