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Pravastatin induces NO synthesis by enhancing microsomal arginine uptake in healthy and preeclamptic placentas
BACKGROUND: Pravastatin, a known inducer of endothelial nitric-oxide synthase (eNOS) was demonstrated in human placenta, however the exact mechanism of it’s action is not fully understood. Since placental NO (nitric oxide) synthesis is of primary importance in the regulation of placental blood flow,...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868828/ https://www.ncbi.nlm.nih.gov/pubmed/31747921 http://dx.doi.org/10.1186/s12884-019-2507-0 |