Cargando…

Immuno-enhancement effects of Platycodon grandiflorum extracts in splenocytes and a cyclophosphamide-induced immunosuppressed rat model

BACKGROUND: Platycodon grandiflorum is a flowering plant that is used in traditional medicine for treating pulmonary and respiratory disorders. It exerts various pharmacological effects, including immunomodulatory and anti-cancer activities. The purpose of this study was to confirm the in vitro and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Noh, Eun-Mi, Kim, Jeong-Mi, Lee, Hak Yong, Song, Hyun-Kyung, Joung, Sang Ok, Yang, Hye Jeong, Kim, Min Jung, Kim, Kang Sung, Lee, Young-Rae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868875/ https://www.ncbi.nlm.nih.gov/pubmed/31752816 http://dx.doi.org/10.1186/s12906-019-2724-0

Ejemplares similares

Immune-enhancing effect of hydrolyzed and fermented Platycodon grandiflorum extract in cyclophosphamide-induced immunosuppressed BALB/c mice
por: Lee, Hyun Sook, et al.
Publicado: (2023)

Effects of Platycodon grandiflorum on Gut Microbiome and Immune System of Immunosuppressed Mouse
por: Jhang, So-Yun, et al.
Publicado: (2021)

Platycodon saponins from Platycodi Radix (Platycodon grandiflorum) for the Green Synthesis of Gold and Silver Nanoparticles
por: Choi, Yoonho, et al.
Publicado: (2018)

Platycosides from the Roots of Platycodon grandiflorum and Their Health Benefits
por: Nyakudya, Elijah, et al.
Publicado: (2014)

Global Profiling of Various Metabolites in Platycodon grandiflorum by UPLC-QTOF/MS
por: Lee, Jae Won, et al.
Publicado: (2015)

Characterization of Saponins from Various Parts of Platycodon grandiflorum Using UPLC-QToF/MS
por: Lee, So-Jeong, et al.
Publicado: (2021)

Immunostimulatory Effect of Zanthoxylum schinifolium-Based Complex Oil Prepared by Supercritical Fluid Extraction in Splenocytes and Cyclophosphamide-Induced Immunosuppressed Rats
por: Lee, Hak Yong, et al.
Publicado: (2018)

accD nuclear transfer of Platycodon grandiflorum and the plastid of early Campanulaceae
por: Hong, Chang Pyo, et al.
Publicado: (2017)

Platyconic Acid A, a Genuine Triterpenoid Saponin from the Roots of Platycodon grandiflorum
por: Choi, Yeon Hee, et al.
Publicado: (2008)

Optimization of extraction condition for platycodin D from Platycodon grandiflorum root and verification of its biological activity
por: Jung, Jihyeon, et al.
Publicado: (2023)

Protective Effects of Platycodon grandiflorum Aqueous Extract on Thioacetamide-induced Fulminant Hepatic Failure in Mice
por: Lim, Jong-Hwan, et al.
Publicado: (2011)

Phenolic Constituents from Platycodon grandiflorum Root and Their Anti-Inflammatory Activity
por: Li, Wei, et al.
Publicado: (2021)

Triterpenoid Saponins Isolated from Platycodon grandiflorum Inhibit Hepatitis C Virus Replication
por: Kim, Jong-Woo, et al.
Publicado: (2013)

Immune-Enhancing Effect of Sargassum horneri on Cyclophosphamide-Induced Immunosuppression in BALB/c Mice and Primary Cultured Splenocytes
por: Kim, Hyo In, et al.
Publicado: (2022)

Chromosome-Scale Genome Assembly and Triterpenoid Saponin Biosynthesis in Korean Bellflower (Platycodon grandiflorum)
por: Lee, Dong-Jun, et al.
Publicado: (2023)

Evaluation of the Spermicidal and Contraceptive Activity of Platycodin D, a Saponin from Platycodon grandiflorum
por: Lu, Zongliang, et al.
Publicado: (2013)

A Systems-Level Analysis of Mechanisms of Platycodon grandiflorum Based on A Network Pharmacological Approach
por: Park, Musun, et al.
Publicado: (2018)

Immunostimulatory activity of hydrolyzed and fermented Platycodon grandiflorum extract occurs via the MAPK and NF-κB signaling pathway in RAW 264.7 cells
por: Jung, Jae In, et al.
Publicado: (2022)

Platycodon grandiflorum Root Protects against Aβ-Induced Cognitive Dysfunction and Pathology in Female Models of Alzheimer’s Disease
por: Nam, Yunkwon, et al.
Publicado: (2021)

Effects of Polysaccharides from Platycodon grandiflorum on Immunity-Enhancing Activity In Vitro
por: Zhao, Xiaona, et al.
Publicado: (2017)

Exploration of Root-associated Bacteria from the Medicinal Plant Platycodon grandiflorum
por: Huang, Cong-Min, et al.
Publicado: (2019)

Chemical Characteristics of Platycodon grandiflorum and its Mechanism in Lung Cancer Treatment
por: Deng, Yaling, et al.
Publicado: (2021)

Polyacylated Anthocyanins in Bluish-Purple Petals of Chinese Bellflower, Platycodon grandiflorum
por: Kondo, Tadao, et al.
Publicado: (2021)

Extract of Platycodon grandiflorum Prevents Doxorubicin-induced Cardiotoxicity in Breast Cancer
por: Shi, Youyang, et al.
Publicado: (2023)

Root Rot of Balloon Flower (Platycodon grandiflorum) Caused by Fusarium solani and Fusarium oxysporum
por: Jeon, Chi Sung, et al.
Publicado: (2013)

Microbial conversion of major ginsenosides in ginseng total saponins by Platycodon grandiflorum endophytes
por: Cui, Lei, et al.
Publicado: (2016)

Platycoside O, a New Triterpenoid Saponin from the Roots of Platycodon grandiflorum
por: Fu, Wen-Wei, et al.
Publicado: (2011)

Platycodon grandiflorum extract: chemical composition and whitening, antioxidant, and anti-inflammatory effects
por: Ma, Xintong, et al.
Publicado: (2021)

Platycodin D, a bioactive component of Platycodon grandiflorum, induces cancer cell death associated with extreme vacuolation
por: Jeon, Daun, et al.
Publicado: (2019)

Improved Bioactivity of 3-O-β-D-Glucopyranosyl Platycosides in Biotransformed Platycodon grandiflorum Root Extract by Pectinase from Aspergillus aculeatus
por: Ju, Jung-Hun, et al.
Publicado: (2021)

Crude Saponin from Platycodon grandiflorum Attenuates Aβ-Induced Neurotoxicity via Antioxidant, Anti-Inflammatory and Anti-Apoptotic Signaling Pathways
por: Ji, Yun-Jeong, et al.
Publicado: (2021)

Immunomodulatory effects of fermented Platycodon grandiflorum extract through NF-κB signaling in RAW 264.7 cells
por: Park, Eun-Jung, et al.
Publicado: (2020)

Candidate Genes Involved in the Biosynthesis of Triterpenoid Saponins in Platycodon grandiflorum Identified by Transcriptome Analysis
por: Ma, Chun-Hua, et al.
Publicado: (2016)

Nontargeted Metabolomic Analysis of Four Different Parts of Platycodon grandiflorum Grown in Northeast China
por: Wang, Cuizhu, et al.
Publicado: (2017)

Platycodon grandiflorum Protects Against Anthracycline-Induced Cardiotoxicity in Early Breast Cancer Patients
por: Hao, Wei, et al.
Publicado: (2020)

Euonymus alatus (Thunb.) Siebold leaf extract enhanced immunostimulatory effects in a cyclophosphamide-induced immunosuppressed rat model
por: Shin, Dong Yeop, et al.
Publicado: (2023)

Orostachys japonicus A. Berger Extracts Induce Immunity-Enhancing Effects on Cyclophosphamide-Treated Immunosuppressed Rats
por: Lee, Hak Yong, et al.
Publicado: (2019)

Transcriptomic Analysis, Cloning, Characterization, and Expression Analysis of Triterpene Biosynthetic Genes and Triterpene Accumulation in the Hairy Roots of Platycodon grandiflorum Exposed to Methyl Jasmonate
por: Kim, Yong-Kyoung, et al.
Publicado: (2021)

Platycoside N: A New Oleanane-Type Triterpenoid Saponin from the Roots of Platycodon grandiflorum
por: Li, Wei, et al.
Publicado: (2010)

Chemical characterization of balloon flower (Platycodon grandiflorum) sprout extracts and their regulation of inflammatory activity in lipopolysaccharide‐stimulated RAW 264.7 murine macrophage cells
por: Kim, Mina, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_oc9auep675ua5vs750be49p9tu