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Arf6-driven endocytic recycling of CD147 determines HCC malignant phenotypes

BACKGROUND: Adhesion molecules distributed on the cell-surface depends upon their dynamic trafficking that plays an important role during cancer progression. ADP-ribosylation factor 6 (Arf6) is a master regulator of membrane trafficking. CD147, a tumor-related adhesive protein, can promote the invas...

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Detalles Bibliográficos
Autores principales: Qi, Shanshan, Su, Linjia, Li, Jing, Zhang, Chuanshan, Ma, Zhe, Liu, Guiqiu, Zhang, Qing, Jia, Guhe, Piao, Yongjun, Zhang, Sihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868876/
https://www.ncbi.nlm.nih.gov/pubmed/31752956
http://dx.doi.org/10.1186/s13046-019-1464-9