ΗΙF1α, EGR1 and SP1 co-regulate the erythropoietin receptor expression under hypoxia: an essential role in the growth of non-small cell lung cancer cells

BACKGROUND: Overexpression of erythropoietin (EPO) and EPO receptor (EPO-R) is associated with poor prognosis in non-small-cell lung carcinoma (NSCLC). Hypoxia, a potent EPO inducer, is a major stimulating factor in the growth of solid tumors. However, how EPO-R expression is regulated under hypoxia...

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Detalles Bibliográficos
Autores principales: Su, Tianhong, Liu, Pi, Ti, Xinyu, Wu, Shouzhen, Xue, Xiaochang, Wang, Zenglu, Dioum, Elhardji, Zhang, Qiuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869211/
https://www.ncbi.nlm.nih.gov/pubmed/31752873
http://dx.doi.org/10.1186/s12964-019-0458-8

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