Dimethyloxaloylglycine-stimulated human bone marrow mesenchymal stem cell-derived exosomes enhance bone regeneration through angiogenesis by targeting the AKT/mTOR pathway

BACKGROUND: Mesenchymal stem cell (MSC)-derived exosomes have been recognized as new candidate agents for treating critical-sized bone defects; they promote angiogenesis and may be an alternative to cell therapy. In this study, we evaluated whether exosomes derived from bone marrow-derived MSCs (BMS...

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Detalles Bibliográficos
Autores principales: Liang, Bo, Liang, Jia-Ming, Ding, Jia-Ning, Xu, Jia, Xu, Jian-Guang, Chai, Yi-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869275/
https://www.ncbi.nlm.nih.gov/pubmed/31747933
http://dx.doi.org/10.1186/s13287-019-1410-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869275/
https://www.ncbi.nlm.nih.gov/pubmed/31747933
http://dx.doi.org/10.1186/s13287-019-1410-y

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