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Phase informed model for motion and susceptibility

Field inhomogeneities caused by variations in magnetic susceptibility throughout the head lead to geometric distortions, mainly in the phase‐encode direction of echo‐planar images (EPI). The magnitude and spatial characteristics of the distortions depend on the orientation of the head in the magneti...

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Detalles Bibliográficos
Autores principales: Hutton, Chloe, Andersson, Jesper, Deichmann, Ralf, Weiskopf, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6870252/
https://www.ncbi.nlm.nih.gov/pubmed/22736546
http://dx.doi.org/10.1002/hbm.22126
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author Hutton, Chloe
Andersson, Jesper
Deichmann, Ralf
Weiskopf, Nikolaus
author_facet Hutton, Chloe
Andersson, Jesper
Deichmann, Ralf
Weiskopf, Nikolaus
author_sort Hutton, Chloe
collection PubMed
description Field inhomogeneities caused by variations in magnetic susceptibility throughout the head lead to geometric distortions, mainly in the phase‐encode direction of echo‐planar images (EPI). The magnitude and spatial characteristics of the distortions depend on the orientation of the head in the magnetic field and will therefore vary with head movement. A new method is presented, based on a phase informed model for motion and susceptibility (PIMMS), which estimates the change in geometric distortion associated with head motion. This method fits a model of the head motion parameters and scanner hardware characteristics to EPI phase time series. The resulting maps of the model fit parameters are used to correct for susceptibility artifacts in the magnitude images. Results are shown for EPI‐based fMRI time‐series acquired at 3T, demonstrating that compared with conventional rigid body realignment, PIMMS removes residual variance associated with motion‐related distortion effects. Furthermore, PIMMS can lead to a reduction in false negatives compared with the widely accepted approach which uses standard rigid body realignment and includes the head motion parameters in the statistical model. The PIMMS method can be used with any standard EPI sequence for which accurate phase information is available. Hum Brain Mapp 34:3086–3100, 2013. © 2012 The Authors. Human Brain Mapping Published byWiley Periodicals, Inc.
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spelling pubmed-68702522020-06-12 Phase informed model for motion and susceptibility Hutton, Chloe Andersson, Jesper Deichmann, Ralf Weiskopf, Nikolaus Hum Brain Mapp Research Articles Field inhomogeneities caused by variations in magnetic susceptibility throughout the head lead to geometric distortions, mainly in the phase‐encode direction of echo‐planar images (EPI). The magnitude and spatial characteristics of the distortions depend on the orientation of the head in the magnetic field and will therefore vary with head movement. A new method is presented, based on a phase informed model for motion and susceptibility (PIMMS), which estimates the change in geometric distortion associated with head motion. This method fits a model of the head motion parameters and scanner hardware characteristics to EPI phase time series. The resulting maps of the model fit parameters are used to correct for susceptibility artifacts in the magnitude images. Results are shown for EPI‐based fMRI time‐series acquired at 3T, demonstrating that compared with conventional rigid body realignment, PIMMS removes residual variance associated with motion‐related distortion effects. Furthermore, PIMMS can lead to a reduction in false negatives compared with the widely accepted approach which uses standard rigid body realignment and includes the head motion parameters in the statistical model. The PIMMS method can be used with any standard EPI sequence for which accurate phase information is available. Hum Brain Mapp 34:3086–3100, 2013. © 2012 The Authors. Human Brain Mapping Published byWiley Periodicals, Inc. John Wiley and Sons Inc. 2012-06-27 /pmc/articles/PMC6870252/ /pubmed/22736546 http://dx.doi.org/10.1002/hbm.22126 Text en Copyright © 2012 The Authors. Human Brain Mapping Published byWiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/3.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Hutton, Chloe
Andersson, Jesper
Deichmann, Ralf
Weiskopf, Nikolaus
Phase informed model for motion and susceptibility
title Phase informed model for motion and susceptibility
title_full Phase informed model for motion and susceptibility
title_fullStr Phase informed model for motion and susceptibility
title_full_unstemmed Phase informed model for motion and susceptibility
title_short Phase informed model for motion and susceptibility
title_sort phase informed model for motion and susceptibility
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6870252/
https://www.ncbi.nlm.nih.gov/pubmed/22736546
http://dx.doi.org/10.1002/hbm.22126
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