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Comparison of an in-house ‘home-brew’ and commercial ViroSeq integrase genotyping assays on HIV-1 subtype C samples

BACKGROUND: Roll-out of Integrase Strand Transfer Inhibitors (INSTIs) such as dolutegravir for HIV combination antiretroviral therapy (cART) in sub-Saharan Africa necessitates the development of affordable HIV drug resistance (HIVDR) assays targeting the Integrase gene. We optimised and evaluated an...

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Detalles Bibliográficos
Autores principales:	Seatla, Kaelo K., Choga, Wonderful T., Mogwele, Mompati, Diphoko, Thabo, Maruapula, Dorcas, Mupfumi, Lucy, Musonda, Rosemary M., Rowley, Christopher F., Avalos, Ava, Kasvosve, Ishmael, Moyo, Sikhulile, Gaseitsiwe, Simani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6871785/ https://www.ncbi.nlm.nih.gov/pubmed/31751353 http://dx.doi.org/10.1371/journal.pone.0224292

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