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Non-enzymatic primer extension with strand displacement

Non-enzymatic RNA self-replication is integral to the emergence of the ‘RNA World’. Despite considerable progress in non-enzymatic template copying, demonstrating a full replication cycle remains challenging due to the difficulty of separating the strands of the product duplex. Here, we report a pre...

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Detalles Bibliográficos
Autores principales:	Zhou, Lijun, Kim, Seohyun Chris, Ho, Katherine H, O'Flaherty, Derek K, Giurgiu, Constantin, Wright, Tom H, Szostak, Jack W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872209/ https://www.ncbi.nlm.nih.gov/pubmed/31702557 http://dx.doi.org/10.7554/eLife.51888

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