Crystal structure of dopamine receptor D4 bound to the subtype selective ligand, L745870

Multiple subtypes of dopamine receptors within the GPCR superfamily regulate neurological processes through various downstream signaling pathways. A crucial question about the dopamine receptor family is what structural features determine the subtype-selectivity of potential drugs. Here, we report t...

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Detalles Bibliográficos
Autores principales: Zhou, Ye, Cao, Can, He, Lingli, Wang, Xianping, Zhang, Xuejun Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872212/
https://www.ncbi.nlm.nih.gov/pubmed/31750832
http://dx.doi.org/10.7554/eLife.48822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872212/
https://www.ncbi.nlm.nih.gov/pubmed/31750832
http://dx.doi.org/10.7554/eLife.48822

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