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Crystal structure of dopamine receptor D4 bound to the subtype selective ligand, L745870

Multiple subtypes of dopamine receptors within the GPCR superfamily regulate neurological processes through various downstream signaling pathways. A crucial question about the dopamine receptor family is what structural features determine the subtype-selectivity of potential drugs. Here, we report t...

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Detalles Bibliográficos
Autores principales:	Zhou, Ye, Cao, Can, He, Lingli, Wang, Xianping, Zhang, Xuejun Cai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872212/ https://www.ncbi.nlm.nih.gov/pubmed/31750832 http://dx.doi.org/10.7554/eLife.48822

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