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Activation of the Human Angiotensin-(1-12)-Chymase Pathway in Rats With Human Angiotensinogen Gene Transcripts

Angiotensin-(1-12) [Ang-(1-12)], an alternate substrate for tissue angiotensin II (Ang II) formation, underscores the importance of alternative renin-independent pathway(s) for the generation of angiotensins. Since renin enzymatic activity is species-specific, a transgenic model of hypertension due...

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Detalles Bibliográficos
Autores principales: Ferrario, Carlos M., VonCannon, Jessica, Ahmad, Sarfaraz, Wright, Kendra N., Roberts, Drew J., Wang, Hao, Yamashita, Tomohisa, Groban, Leanne, Cheng, Che Ping, Collawn, James F., Dell'Italia, Louis J., Varagic, Jasmina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872498/
https://www.ncbi.nlm.nih.gov/pubmed/31803758
http://dx.doi.org/10.3389/fcvm.2019.00163