Refining the Mouse Subtotal Nephrectomy in Male 129S2/SV Mice for Consistent Modeling of Progressive Kidney Disease With Renal Inflammation and Cardiac Dysfunction

Chronic kidney disease (CKD) is prevalent worldwide and is associated with significant co-morbidities including cardiovascular disease (CVD). Traditionally, the subtotal nephrectomy (remnant kidney) experimental model has been performed in rats to model progressive renal disease. The model experimen...

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Detalles Bibliográficos
Autores principales: O’Sullivan, James, Finnie, Sarah Louise, Teenan, Oliver, Cairns, Carolynn, Boyd, Andrew, Bailey, Matthew A., Thomson, Adrian, Hughes, Jeremy, Bénézech, Cécile, Conway, Bryan Ronald, Denby, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872545/
https://www.ncbi.nlm.nih.gov/pubmed/31803059
http://dx.doi.org/10.3389/fphys.2019.01365

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