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Single variable domains from the T cell receptor β chain function as mono- and bifunctional CARs and TCRs

Cell therapy using T cell receptors (TCRs) and chimeric antigen receptors (CARs) represents a new wave of immunotherapies garnering considerable attention and investment. Further progress in this area of medicine depends in part on improving the functional capabilities of the engineered components,...

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Detalles Bibliográficos
Autores principales:	Oh, Julyun, Warshaviak, Dora Toledo, Mkrtichyan, Mikayel, Munguia, Melanie Lisette, Lin, Abby, Chai, Falene, Pigott, Craig, Kang, Jaspal, Gallo, Michael, Kamb, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872726/ https://www.ncbi.nlm.nih.gov/pubmed/31754147 http://dx.doi.org/10.1038/s41598-019-53756-4

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