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Phenotypic transitions enacted by simulated microgravity do not alter coherence in gene transcription profile
Cells in simulated microgravity undergo a reversible morphology switch, causing the appearance of two distinct phenotypes. Despite the dramatic splitting into an adherent-fusiform and a floating-spherical population, when looking at the gene-expression phase space, cell transition ends up in a large...
Autores principales: | Po, Agnese, Giuliani, Alessandro, Masiello, Maria Grazia, Cucina, Alessandra, Catizone, Angela, Ricci, Giulia, Chiacchiarini, Martina, Tafani, Marco, Ferretti, Elisabetta, Bizzarri, Mariano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872750/ https://www.ncbi.nlm.nih.gov/pubmed/31799378 http://dx.doi.org/10.1038/s41526-019-0088-x |
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