Targeted delivery of lysosomal enzymes to the endocytic compartment in human cells using engineered extracellular vesicles

Targeted delivery of lysosomal enzymes to the endocytic compartment of human cells represents a transformative technology for treating a large family of lysosomal storage diseases (LSDs). Gaucher disease is one of the most common types of LSDs caused by mutations to the lysosomal β-glucocerebrosidas...

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Detalles Bibliográficos
Autores principales: Do, Mai Anh, Levy, Daniel, Brown, Annie, Marriott, Gerard, Lu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872767/
https://www.ncbi.nlm.nih.gov/pubmed/31754156
http://dx.doi.org/10.1038/s41598-019-53844-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872767/
https://www.ncbi.nlm.nih.gov/pubmed/31754156
http://dx.doi.org/10.1038/s41598-019-53844-5

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