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Targeted delivery of lysosomal enzymes to the endocytic compartment in human cells using engineered extracellular vesicles
Targeted delivery of lysosomal enzymes to the endocytic compartment of human cells represents a transformative technology for treating a large family of lysosomal storage diseases (LSDs). Gaucher disease is one of the most common types of LSDs caused by mutations to the lysosomal β-glucocerebrosidas...
Autores principales: | Do, Mai Anh, Levy, Daniel, Brown, Annie, Marriott, Gerard, Lu, Biao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872767/ https://www.ncbi.nlm.nih.gov/pubmed/31754156 http://dx.doi.org/10.1038/s41598-019-53844-5 |
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