PODXL1 promotes metastasis of the pancreatic ductal adenocarcinoma by activating the C5aR/C5a axis from the tumor microenvironment

Pancreatic invasive ductal adenocarcinoma (PDAC) is a representative intractable malignancy under the current cancer therapies, and is considered a scirrhous carcinoma because it develops dense stroma. Both PODXL1, a member of CD34 family molecules, and C5aR, a critical cell motility inducer, have g...

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Detalles Bibliográficos
Autores principales: Saito, Ken, Iioka, Hidekazu, Maruyama, Satoshi, Sumardika, I. Wayan, Sakaguchi, Masakiyo, Kondo, Eisaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872781/
https://www.ncbi.nlm.nih.gov/pubmed/31759250
http://dx.doi.org/10.1016/j.neo.2019.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872781/
https://www.ncbi.nlm.nih.gov/pubmed/31759250
http://dx.doi.org/10.1016/j.neo.2019.09.003

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