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Myc/Max dependent intronic long antisense noncoding RNA, EVA1A-AS, suppresses the expression of Myc/Max dependent anti-proliferating gene EVA1A in a U2 dependent manner

The Myc gene has been implicated in the pathogenesis of most types of human cancerous tumors. Myc/Max activates large numbers of pro-tumor genes; however it also induces anti-proliferation genes. When anti-proliferation genes are activated by Myc, cancer cells can only survive if they are downregula...

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Detalles Bibliográficos
Autores principales: Niehus, Svenja E., Allister, Aldrige B., Hoffmann, Andrea, Wiehlmann, Lutz, Tamura, Teruko, Tran, Doan Duy Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872820/
https://www.ncbi.nlm.nih.gov/pubmed/31754186
http://dx.doi.org/10.1038/s41598-019-53944-2