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Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin

A possible role for calcium signalling in the autosomal dominant form of dementia, familial encephalopathy with neuroserpin inclusion bodies (FENIB), has been proposed, which may point towards a mechanism by which cells could sense and respond to the accumulation of mutant serpin polymers in the end...

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Detalles Bibliográficos
Autores principales: Malintan, Nancy T., Buckingham, Steven D., Lomas, David A., Sattelle, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872872/
https://www.ncbi.nlm.nih.gov/pubmed/31754242
http://dx.doi.org/10.1038/s41598-019-53535-1