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Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin
A possible role for calcium signalling in the autosomal dominant form of dementia, familial encephalopathy with neuroserpin inclusion bodies (FENIB), has been proposed, which may point towards a mechanism by which cells could sense and respond to the accumulation of mutant serpin polymers in the end...
Autores principales: | Malintan, Nancy T., Buckingham, Steven D., Lomas, David A., Sattelle, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872872/ https://www.ncbi.nlm.nih.gov/pubmed/31754242 http://dx.doi.org/10.1038/s41598-019-53535-1 |
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