Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy

We report a case of bilateral serous retinal detachment in a patient with rod-cone dystrophy caused by mutation of BEST1. This followed creatine monohydrate use as a dietary supplement. A 39-year-old male with rod-cone dystrophy and low hyperopia developed extensive bilateral exudative retinal detac...

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Autores principales: Kopsidas, Konstantinos, Javidi, Hedayat, Kelly, Simon P., Aslam, Tariq, Black, Graeme, Mahmood, Sajjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873073/
https://www.ncbi.nlm.nih.gov/pubmed/31762771
http://dx.doi.org/10.1159/000503853
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author Kopsidas, Konstantinos
Javidi, Hedayat
Kelly, Simon P.
Aslam, Tariq
Black, Graeme
Mahmood, Sajjad
author_facet Kopsidas, Konstantinos
Javidi, Hedayat
Kelly, Simon P.
Aslam, Tariq
Black, Graeme
Mahmood, Sajjad
author_sort Kopsidas, Konstantinos
collection PubMed
description We report a case of bilateral serous retinal detachment in a patient with rod-cone dystrophy caused by mutation of BEST1. This followed creatine monohydrate use as a dietary supplement. A 39-year-old male with rod-cone dystrophy and low hyperopia developed extensive bilateral exudative retinal detachment following creatine monohydrate diet supplementation. Five days after stopping creatine use, the bilateral retinal detachments resolved completely. This may indicate a causative relation of creatine supplementation to development of serous retinal detachment in a susceptible patient with pre-existing retinal dystrophy.
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spelling pubmed-68730732019-11-22 Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy Kopsidas, Konstantinos Javidi, Hedayat Kelly, Simon P. Aslam, Tariq Black, Graeme Mahmood, Sajjad Case Rep Ophthalmol Case Report We report a case of bilateral serous retinal detachment in a patient with rod-cone dystrophy caused by mutation of BEST1. This followed creatine monohydrate use as a dietary supplement. A 39-year-old male with rod-cone dystrophy and low hyperopia developed extensive bilateral exudative retinal detachment following creatine monohydrate diet supplementation. Five days after stopping creatine use, the bilateral retinal detachments resolved completely. This may indicate a causative relation of creatine supplementation to development of serous retinal detachment in a susceptible patient with pre-existing retinal dystrophy. S. Karger AG 2019-11-01 /pmc/articles/PMC6873073/ /pubmed/31762771 http://dx.doi.org/10.1159/000503853 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Kopsidas, Konstantinos
Javidi, Hedayat
Kelly, Simon P.
Aslam, Tariq
Black, Graeme
Mahmood, Sajjad
Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy
title Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy
title_full Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy
title_fullStr Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy
title_full_unstemmed Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy
title_short Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy
title_sort unique case of bilateral exudative retinal detachment following creatine supplementation in a patient with autosomal dominant bestrophinopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873073/
https://www.ncbi.nlm.nih.gov/pubmed/31762771
http://dx.doi.org/10.1159/000503853
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