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Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation

Epilepsy is a common neurological disorder characterized by recurrent and unprovoked seizures thought to arise from impaired balance between neuronal excitation and inhibition. Our understanding of the neurophysiological mechanisms that render the brain epileptogenic remains incomplete, reflected by...

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Detalles Bibliográficos
Autores principales: Duy, Phan Q., David, Wyatt B., Kahle, Kristopher T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873151/
https://www.ncbi.nlm.nih.gov/pubmed/31803025
http://dx.doi.org/10.3389/fncel.2019.00515