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Infectious disease outbreaks in the African region: overview of events reported to the World Health Organization in 2018

The WHO African region is characterised by the largest infectious disease burden in the world. We conducted a retrospective descriptive analysis using records of all infectious disease outbreaks formally reported to the WHO in 2018 by Member States of the African region. We analysed the spatio-tempo...

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Autores principales: Mboussou, F., Ndumbi, P., Ngom, R., Kamassali, Z., Ogundiran, O., Van Beek, J., Williams, G., Okot, C., Hamblion, E. L., Impouma, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873157/
https://www.ncbi.nlm.nih.gov/pubmed/31709961
http://dx.doi.org/10.1017/S0950268819001912
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author Mboussou, F.
Ndumbi, P.
Ngom, R.
Kamassali, Z.
Ogundiran, O.
Van Beek, J.
Williams, G.
Okot, C.
Hamblion, E. L.
Impouma, B.
author_facet Mboussou, F.
Ndumbi, P.
Ngom, R.
Kamassali, Z.
Ogundiran, O.
Van Beek, J.
Williams, G.
Okot, C.
Hamblion, E. L.
Impouma, B.
author_sort Mboussou, F.
collection PubMed
description The WHO African region is characterised by the largest infectious disease burden in the world. We conducted a retrospective descriptive analysis using records of all infectious disease outbreaks formally reported to the WHO in 2018 by Member States of the African region. We analysed the spatio-temporal distribution, the notification delay as well as the morbidity and mortality associated with these outbreaks. In 2018, 96 new disease outbreaks were reported across 36 of the 47 Member States. The most commonly reported disease outbreak was cholera which accounted for 20.8% (n = 20) of all events, followed by measles (n = 11, 11.5%) and Yellow fever (n = 7, 7.3%). About a quarter of the outbreaks (n = 23) were reported following signals detected through media monitoring conducted at the WHO regional office for Africa. The median delay between the disease onset and WHO notification was 16 days (range: 0–184). A total of 107 167 people were directly affected including 1221 deaths (mean case fatality ratio (CFR): 1.14% (95% confidence interval (CI) 1.07%–1.20%)). The highest CFR was observed for diseases targeted for eradication or elimination: 3.45% (95% CI 0.89%–10.45%). The African region remains prone to outbreaks of infectious diseases. It is therefore critical that Member States improve their capacities to rapidly detect, report and respond to public health events.
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spelling pubmed-68731572019-12-04 Infectious disease outbreaks in the African region: overview of events reported to the World Health Organization in 2018 Mboussou, F. Ndumbi, P. Ngom, R. Kamassali, Z. Ogundiran, O. Van Beek, J. Williams, G. Okot, C. Hamblion, E. L. Impouma, B. Epidemiol Infect Original Paper The WHO African region is characterised by the largest infectious disease burden in the world. We conducted a retrospective descriptive analysis using records of all infectious disease outbreaks formally reported to the WHO in 2018 by Member States of the African region. We analysed the spatio-temporal distribution, the notification delay as well as the morbidity and mortality associated with these outbreaks. In 2018, 96 new disease outbreaks were reported across 36 of the 47 Member States. The most commonly reported disease outbreak was cholera which accounted for 20.8% (n = 20) of all events, followed by measles (n = 11, 11.5%) and Yellow fever (n = 7, 7.3%). About a quarter of the outbreaks (n = 23) were reported following signals detected through media monitoring conducted at the WHO regional office for Africa. The median delay between the disease onset and WHO notification was 16 days (range: 0–184). A total of 107 167 people were directly affected including 1221 deaths (mean case fatality ratio (CFR): 1.14% (95% confidence interval (CI) 1.07%–1.20%)). The highest CFR was observed for diseases targeted for eradication or elimination: 3.45% (95% CI 0.89%–10.45%). The African region remains prone to outbreaks of infectious diseases. It is therefore critical that Member States improve their capacities to rapidly detect, report and respond to public health events. Cambridge University Press 2019-11-11 /pmc/articles/PMC6873157/ /pubmed/31709961 http://dx.doi.org/10.1017/S0950268819001912 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike licence (http://creativecommons.org/licenses/by-nc-sa/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons licence is included and the original work is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use.
spellingShingle Original Paper
Mboussou, F.
Ndumbi, P.
Ngom, R.
Kamassali, Z.
Ogundiran, O.
Van Beek, J.
Williams, G.
Okot, C.
Hamblion, E. L.
Impouma, B.
Infectious disease outbreaks in the African region: overview of events reported to the World Health Organization in 2018
title Infectious disease outbreaks in the African region: overview of events reported to the World Health Organization in 2018
title_full Infectious disease outbreaks in the African region: overview of events reported to the World Health Organization in 2018
title_fullStr Infectious disease outbreaks in the African region: overview of events reported to the World Health Organization in 2018
title_full_unstemmed Infectious disease outbreaks in the African region: overview of events reported to the World Health Organization in 2018
title_short Infectious disease outbreaks in the African region: overview of events reported to the World Health Organization in 2018
title_sort infectious disease outbreaks in the african region: overview of events reported to the world health organization in 2018
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873157/
https://www.ncbi.nlm.nih.gov/pubmed/31709961
http://dx.doi.org/10.1017/S0950268819001912
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